(1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID
Synonym(s):(−)-Camphoric acid;(1S,3R)-1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid
- CAS NO.：560-09-8
- Empirical Formula: C10H16O4
- Molecular Weight: 200.23
- MDL number: MFCD00064937
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID?
Chemical properties
White Solid
The Uses of (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID
(1S,3R)-(?)-Camphoric acid can be used:
- As an enantiomeric linker in the preparation of chiral surface-anchored metal-organic frameworks (MOFs).
- To prepare porous MOFs having multifunctional properties; used in gas adsorption and separation of racemic alcohols.
- To prepare a cobalt(II) coordination polymer named {Co(phen)(H2O)[C8H14(COO)2]}n·(CH3OH)n , wherein “phen” is 1,10-phenanthroline and C8H14(COOH)2 is [(1S,3R)-camphoric acid.
storage
+4°C
Purification Methods
Purify the acid by re-precipitation from an alkaline solution by HCl, filter it off, and recrystallise it from water several times, rejecting the first crop. It forms leaflets from EtOH and Me2CO and H2O and is insoluble in CHCl3. Its solubility in H2O is 0.8% at 25o and 10% at 100o, 50% in EtOH and 5% in ethylene glycol. The (±)-acid has m 202-203o. The (+)-1-methyl ester has m 86o (from pet ether) [] 20 +45o (c 4, EtOH), and the (+)-3-methyl ester has m 77o (from pet ether) []17.5 +53.9o (c 3, EtOH). [Rupe & Thommen Helv Chim Acta 30 933
Properties of (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID
| Melting point: | 188-190 °C(lit.) |
| Boiling point: | 312.0±25.0 °C(Predicted) |
| Density | 1.177±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO, Ethanol, Methanol |
| form | Solid |
| pka | 4.57±0.60(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D 48°, c = 10 in ethanol |
| BRN | 1874674 |
| CAS DataBase Reference | 560-09-8(CAS DataBase Reference) |
Safety information for (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (1S,3R)-1,2,2-TRIMETHYL-1,3-CYCLOPENTANEDICARBOXYLIC ACID
New Products
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