(1R)-(-)-(10-Camphorsulfonyl)oxaziridine

Synonym(s):(1R)-(−)-(Camphorylsulfonyl)oxaziridine;(1R)-(−)-2,N-Epoxy-exo-10,2-bornanesultam

CAS NO.：104372-31-8
Empirical Formula: C10H15NO3S
Molecular Weight: 229.3
MDL number: MFCD00075428
EINECS: 800-131-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-08-17 18:11:45

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine Structural

What is (1R)-(-)-(10-Camphorsulfonyl)oxaziridine?

Chemical properties

White crystalline powder

The Uses of (1R)-(-)-(10-Camphorsulfonyl)oxaziridine

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine is a useful synthetic intermediate. Used for asymmetric hydroxylation.

The Uses of (1R)-(-)-(10-Camphorsulfonyl)oxaziridine

Reactant involved in:

Asymmetric synthesis of proton pump inhibitors
Asymmetric synthesis of polyhydroxylated pyrrolidines
Diastereoselective hydroxylation of chlorophylls a and b enolate anions

Used in impregnated silica nanoparticles for removal of sulfur mustard from wastewater

Used to modify blebbistatin for investigations of myosin inhibitor design

What are the applications of Application

(1R)-(?)-(10-Camphorsulfonyl)oxaziridine is a useful synthetic intermediate used for asymmetric hydroxylation

Properties of (1R)-(-)-(10-Camphorsulfonyl)oxaziridine

Melting point:	170-174 °C
Boiling point:	317.6±25.0 °C(Predicted)
alpha	-46.6 º (c=2, CHCl3 25 ºC)
Density	1.2486 (rough estimate)
refractive index	1.5060 (estimate)
Flash point:	170℃
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Powder
pka	-11.75±0.40(Predicted)
color	White
optical activity	[α]20/D 44°, c = 2.2 in chloroform
BRN	6274369
CAS DataBase Reference	104372-31-8(CAS DataBase Reference)

Safety information for (1R)-(-)-(10-Camphorsulfonyl)oxaziridine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.