1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

Synonym(s):1a,10b-Dihydro-6H-dibenzo(b,f)oxireno[d]azepine-6-carboxamide

CAS NO.：36507-30-9
Empirical Formula: C15H12N2O2
Molecular Weight: 252.27
MDL number: MFCD00467137
EINECS: 641-693-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-06 18:33:45

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Structural

What is 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE?

Chemical properties

White Solid

The Uses of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC

The Uses of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.

The Uses of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.

What are the applications of Application

Carbamazepine 10,11-Epoxide is a Carbamazepine metabolite

Definition

ChEBI: An epoxide and metabolite of carbamazepine.

General Description

Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.

Biochem/physiol Actions

First metabolite of carbamazepine

Properties of 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

Melting point:	204-206°C
Boiling point:	390.2±52.0 °C(Predicted)
Density	1.377±0.06 g/cm3(Predicted)
Flash point:	9℃
storage temp.	-20°C
solubility	Chloroform (Slightly), DMSO (Slightly)
form	neat
pka	13.91±0.20(Predicted)
form	Solid
color	White

Safety information for 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

Signal word	Danger
Pictogram(s)	Environment GHS09
GHS Hazard Statements	H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment.