10,11-DIHYDROCARBAMAZEPINE

Synonym(s):10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide;10,11-Dihydrocarbamazepine

CAS NO.：3564-73-6
Empirical Formula: C15H14N2O
Molecular Weight: 238.28
MDL number: MFCD00005072
EINECS: 222-649-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-08 20:21:46

What is 10,11-DIHYDROCARBAMAZEPINE?

Chemical properties

white crystals or needles

The Uses of 10,11-DIHYDROCARBAMAZEPINE

10,11-Dihydrocarbamazepine is used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It can be used in chemiluminescence method for determination of carbamazepine.

The Uses of 10,11-DIHYDROCARBAMAZEPINE

A dihydro impurity of Carbamazepine (C175840)

What are the applications of Application

10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug

General Description

10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.

Properties of 10,11-DIHYDROCARBAMAZEPINE

Melting point:	205-210 °C(lit.)
Boiling point:	394.5±52.0 °C(Predicted)
Density	1.232±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	dichloromethane: soluble2.5%, clear, colorless
form	neat
pka	14.07±0.20(Predicted)
form	Solid
color	White to Off-White
Water Solubility	Soluble in dichloromethane. Insoluble in water.
BRN	196969

Safety information for 10,11-DIHYDROCARBAMAZEPINE

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H336:Specific target organ toxicity,single exposure; Narcotic effects
Precautionary Statement Codes	P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention.