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HomeProduct name list17-OCTADECYNOIC ACID

17-OCTADECYNOIC ACID

Synonym(s):17-ODYA;Alkynyl Stearic Acid;Octadec-17-ynoic acid

17-OCTADECYNOIC ACID Structural

What is 17-OCTADECYNOIC ACID?

Description

Alkynyl stearic acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry.

The Uses of 17-OCTADECYNOIC ACID

17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase.

What are the applications of Application

17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase

Definition

ChEBI: Octadec-17-ynoic acid is an acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid. It has a role as a P450 inhibitor, an EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor and an EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor. It is a long-chain fatty acid, an acetylenic fatty acid, a terminal acetylenic compound and a monounsaturated fatty acid.

Biological Activity

Potent suicide inhibitor of LTB 4 ω -hydroxylase.

Biochem/physiol Actions

17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism.

storage

Store at -20°C

Properties of 17-OCTADECYNOIC ACID

Boiling point: 400.8±18.0 °C(Predicted)
Density  0.922±0.06 g/cm3(Predicted)
storage temp.  Store at RT
solubility  Soluble to 50 mM in ethanol and to 100 mM in DMSO
form  White solid.
pka 4.78±0.10(Predicted)
color  White to off-white
CAS DataBase Reference 34450-18-5(CAS DataBase Reference)

Safety information for 17-OCTADECYNOIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 17-OCTADECYNOIC ACID

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