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HomeProduct name list17β-Estradiol 3-O-Sulfate SodiuM Salt

17β-Estradiol 3-O-Sulfate SodiuM Salt

Synonym(s):1,3,5(10)-Estratriene-3,17β-diol 3-sulfate;3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate

17β-Estradiol 3-O-Sulfate SodiuM Salt Structural

What is 17β-Estradiol 3-O-Sulfate SodiuM Salt?

The Uses of 17β-Estradiol 3-O-Sulfate SodiuM Salt

17β-Estradiol 3-O-Sulfate Sodium Salt is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.

The Uses of 17β-Estradiol 3-O-Sulfate SodiuM Salt

β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.

General Description

β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.

Biochem/physiol Actions

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

Properties of 17β-Estradiol 3-O-Sulfate SodiuM Salt

Melting point: 207 °C
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  White to Off-White
Stability: Hygroscopic

Safety information for 17β-Estradiol 3-O-Sulfate SodiuM Salt

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H351:Carcinogenicity
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for 17β-Estradiol 3-O-Sulfate SodiuM Salt

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