17β-Estradiol 3-O-Sulfate SodiuM Salt
Synonym(s):1,3,5(10)-Estratriene-3,17β-diol 3-sulfate;3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate
- CAS NO.：4999-79-5
- Empirical Formula: C18H23NaO5S
- Molecular Weight: 374.43
- MDL number: MFCD00056553
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 17β-Estradiol 3-O-Sulfate SodiuM Salt?
The Uses of 17β-Estradiol 3-O-Sulfate SodiuM Salt
17β-Estradiol 3-O-Sulfate Sodium Salt is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.
The Uses of 17β-Estradiol 3-O-Sulfate SodiuM Salt
β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.
General Description
β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.
Biochem/physiol Actions
β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.
Properties of 17β-Estradiol 3-O-Sulfate SodiuM Salt
| Melting point: | 207 °C |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for 17β-Estradiol 3-O-Sulfate SodiuM Salt
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H351:Carcinogenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 17β-Estradiol 3-O-Sulfate SodiuM Salt
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(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE ACICLOVIR AMLODIPINE SODIUM METHYL PARABEN Methylcobalamin (vitamin B12) SODIUM VALPROATE 5-Fluoro-2-iodo-3-methylaniline Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 3-Bromo-2-hydroxybenzeneacetic acid 5-Iodo-3-methyl-2-nitropyridine 1-(3-Chloro-2-hydroxyphenyl)-2-propanoneRelated products of tetrahydrofuran
![1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL DISULFATE DIPOTASSIUM SALT](https://img.chemicalbook.in/CAS/GIF/17046-60-5.gif)
![1,3,5[10]-ESTRATRIENE-3,16ALPHA,17BETA-TRIOL 3-SULFATE SODIUM SALT](https://img.chemicalbook.in/CAS/GIF/5150-64-1.gif)
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