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HomeProduct name list13,14-DIHYDROPROSTAGLANDIN E1

13,14-DIHYDROPROSTAGLANDIN E1

Synonym(s):(9α,11α,13E,15S)-9,11,15-Trihydroxy-6-oxoprosta-13-en-1-oic acid;6-Ketoprostaglandin F;6-Oxo-prostaglandin F

13,14-DIHYDROPROSTAGLANDIN E1 Structural

What is 13,14-DIHYDROPROSTAGLANDIN E1?

Description

6-keto prostaglandin F (6-keto PGF) is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF.

The Uses of 13,14-DIHYDROPROSTAGLANDIN E1

6-Ketoprostaglandin F1α is the stable hydrolysis product of prostacyclin (P839060), an eicosanoid which prevents the formation of platelet plugs and an effective vasodilator.

What are the applications of Application

6-Keto-prostaglandin F1α is a PGI 2 hydrolysis product used as a marker for PGI 2

Definition

ChEBI: A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.

Properties of 13,14-DIHYDROPROSTAGLANDIN E1

Boiling point: 575.3±50.0 °C(Predicted)
Density  1.191±0.06 g/cm3(Predicted)
RTECS  UK8428300
storage temp.  −20°C
solubility  ethanol: 10 mg/mL, clear, faintly yellow
pka 4.69±0.10(Predicted)
form  White to off-white solid.
BRN  2821925

Safety information for 13,14-DIHYDROPROSTAGLANDIN E1

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P321:Specific treatment (see … on this label).
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

Computed Descriptors for 13,14-DIHYDROPROSTAGLANDIN E1

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