1,3-DiMethyl-6-aMino-1H-indazole
- CAS NO.：221681-92-1
- Empirical Formula: C9H11N3
- Molecular Weight: 161.2
- MDL number: MFCD18432764
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-08-26 12:11:55
What is 1,3-DiMethyl-6-aMino-1H-indazole?
The Uses of 1,3-DiMethyl-6-aMino-1H-indazole
1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR. It is used as a reagent in the preparation of glycinamide derivatives which are useful in production of drugs for preventing and treating diseases caused by S-adenosyl homocysteine hydrolase.
Properties of 1,3-DiMethyl-6-aMino-1H-indazole
| Boiling point: | 335.4±22.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 3.93±0.50(Predicted) |
Safety information for 1,3-DiMethyl-6-aMino-1H-indazole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H320:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,3-DiMethyl-6-aMino-1H-indazole
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