1,3-bis(3-glycidoxypropyl)tetramethyldisiloxane

CAS NO.：126-80-7
Empirical Formula: C16H34O5Si2
Molecular Weight: 362.61
MDL number: MFCD00039672
EINECS: 204-803-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-02 14:41:18

What is 1,3-bis(3-glycidoxypropyl)tetramethyldisiloxane?

The Uses of 1,3-bis(3-glycidoxypropyl)tetramethyldisiloxane

1,3-Bis(3-glycidyloxypropyl)tetramethyldisiloxane can be used:

As a starting material to synthesize functional poly(siloxane amine)s via an amine-epoxy click polymerization for material and biological applications.
To prepare polymer electrolyte membranes (PEM) for fuel cell applications.

Synthesis

1,1,3,3-Tetramethyldisiloxane and 1.1 equiv of allyl glycidyl ether (calculated to each Si-H group) were placed into the reaction vessel and heated up to 90 °C. Then the appropriate amount of [{Rh(OSiMe3)cod}2] (in the ratio 10-5 mol per mol Si-H) was added as a catalyst, and the reaction was continued for the next 2 h to give a crude product 1,3-bis(3-glycidoxypropyl)tetramethyldisiloxane.

Properties of 1,3-bis(3-glycidoxypropyl)tetramethyldisiloxane

Melting point:	<0°C
Boiling point:	184 °C2 mm Hg(lit.)
Density	0.996 g/mL at 20 °C(lit.)
refractive index	n20/D 1.452
Flash point:	110°C
Specific Gravity	0.996
Hydrolytic Sensitivity	3: reacts with aqueous base
BRN	223966
InChI	InChI=1S/C16H34O5Si2/c1-22(2,9-5-7-17-11-15-13-19-15)21-23(3,4)10-6-8-18-12-16-14-20-16/h15-16H,5-14H2,1-4H3
EPA Substance Registry System	1,1,3,3-Tetramethyl-1,3-bis[3-glycidyloxypropyl]disiloxane (126-80-7)

Safety information for 1,3-bis(3-glycidoxypropyl)tetramethyldisiloxane

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.