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HomeProduct name list1,2,5,8-TETRAHYDROXYANTHRAQUINONE

1,2,5,8-TETRAHYDROXYANTHRAQUINONE

Synonym(s):1,2,5,8- Tetra hydroxy-9,10- anthra quinone;1,2,5,8-Tetrahydroxy-9,10-anthraquinone;1,2,5,8-Tetrahydroxy-9,10-anthraquinone;1,2,5,8-Tetrahydroxyanthraquinone;Alizarin Bordeaux BD

  • CAS NO.:81-61-8
  • Empirical Formula: C14H8O6
  • Molecular Weight: 272.21
  • MDL number: MFCD00001205
  • EINECS: 201-366-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
1,2,5,8-TETRAHYDROXYANTHRAQUINONE Structural

What is 1,2,5,8-TETRAHYDROXYANTHRAQUINONE?

The Uses of 1,2,5,8-TETRAHYDROXYANTHRAQUINONE

1,2,5,8-TETRAHYDROXYANTHRAQUINONE is Al salts dark red, cotton mordanted with Cr salts bluish-violet. No longer used as a dye, except occasionally in printing cotton.

Definition

ChEBI: A tetrahydroxyanthraquinone having the four hydroxy groups at the 1-, 2-, 5- and 8-positions.

Preparation

Quinalizarin. 1,2-Dihydroxyanthracene-9,10-dione or 1,4-Dihydroxyanthracene-9,10-dione with great excess fuming sulfuric acid oxidation and hydrolysis.

Biochem/physiol Actions

Quinalizarin is a potent (IC50 = 110 nM), ATP-competitive, and highly selective (IC50 >1μM against CK1 and 72 other kinases) casein Kinase II (CK2) inhibitor.

Purification Methods

Crystallise the quinone from acetic acid or nitrobenzene. It can be sublimed in vacuo. The Cu salt forms red crystals. [Beilstein 8 H 549, 8 I 755, 8 II 584.]

Properties and Applications

violet (chromium), dark red light purple (aluminum). Soluble in ethanol. In concentrated sulfuric acid for blue purple, dilution after dark red precipitation.

Standard Ironing Fastness Light Fastness Fulling Persperation Fastness Soaping Water
Alkali Acid
ISO 6 4-5 5 4-5

Properties of 1,2,5,8-TETRAHYDROXYANTHRAQUINONE

Melting point: ≥300 °C
Boiling point: 375.27°C (rough estimate)
Density  1.4292 (rough estimate)
refractive index  1.5230 (estimate)
storage temp.  room temp
form  powder
Colour Index  58500
color  red
Water Solubility  2.586mg/L(25 ºC)
BRN  1889617
CAS DataBase Reference 81-61-8(CAS DataBase Reference)
EPA Substance Registry System 9,10-Anthracenedione, 1,2,5,8-tetrahydroxy- (81-61-8)

Safety information for 1,2,5,8-TETRAHYDROXYANTHRAQUINONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P391:Collect spillage. Hazardous to the aquatic environment
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for 1,2,5,8-TETRAHYDROXYANTHRAQUINONE

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