1,2,5,8-TETRAHYDROXYANTHRAQUINONE
Synonym(s):1,2,5,8- Tetra hydroxy-9,10- anthra quinone;1,2,5,8-Tetrahydroxy-9,10-anthraquinone;1,2,5,8-Tetrahydroxy-9,10-anthraquinone;1,2,5,8-Tetrahydroxyanthraquinone;Alizarin Bordeaux BD
- CAS NO.：81-61-8
- Empirical Formula: C14H8O6
- Molecular Weight: 272.21
- MDL number: MFCD00001205
- EINECS: 201-366-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 1,2,5,8-TETRAHYDROXYANTHRAQUINONE?
The Uses of 1,2,5,8-TETRAHYDROXYANTHRAQUINONE
1,2,5,8-TETRAHYDROXYANTHRAQUINONE is Al salts dark red, cotton mordanted with Cr salts bluish-violet. No longer used as a dye, except occasionally in printing cotton.
Definition
ChEBI: A tetrahydroxyanthraquinone having the four hydroxy groups at the 1-, 2-, 5- and 8-positions.
Preparation
Quinalizarin. 1,2-Dihydroxyanthracene-9,10-dione or 1,4-Dihydroxyanthracene-9,10-dione with great excess fuming sulfuric acid oxidation and hydrolysis.
Biochem/physiol Actions
Quinalizarin is a potent (IC50 = 110 nM), ATP-competitive, and highly selective (IC50 >1μM against CK1 and 72 other kinases) casein Kinase II (CK2) inhibitor.
Purification Methods
Crystallise the quinone from acetic acid or nitrobenzene. It can be sublimed in vacuo. The Cu salt forms red crystals. [Beilstein 8 H 549, 8 I 755, 8 II 584.]
Properties and Applications
violet (chromium), dark red light purple (aluminum). Soluble in ethanol. In concentrated sulfuric acid for blue purple, dilution after dark red precipitation.
| Standard | Ironing Fastness | Light Fastness | Fulling | Persperation Fastness | Soaping | Water | |
| Alkali | Acid | ||||||
| ISO | 6 | 4-5 | 5 | 4-5 | |||
Properties of 1,2,5,8-TETRAHYDROXYANTHRAQUINONE
| Melting point: | ≥300 °C |
| Boiling point: | 375.27°C (rough estimate) |
| Density | 1.4292 (rough estimate) |
| refractive index | 1.5230 (estimate) |
| storage temp. | room temp |
| form | powder |
| Colour Index | 58500 |
| color | red |
| Water Solubility | 2.586mg/L(25 ºC) |
| BRN | 1889617 |
| CAS DataBase Reference | 81-61-8(CAS DataBase Reference) |
| EPA Substance Registry System | 9,10-Anthracenedione, 1,2,5,8-tetrahydroxy- (81-61-8) |
Safety information for 1,2,5,8-TETRAHYDROXYANTHRAQUINONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P391:Collect spillage. Hazardous to the aquatic environment P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 1,2,5,8-TETRAHYDROXYANTHRAQUINONE
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