1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
- CAS NO.：154130-99-1
- Empirical Formula: C18H22N2O
- Molecular Weight: 282.38
- MDL number: MFCD00924135
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
![1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE Structural](https://img.chemicalbook.in/CAS/GIF/154130-99-1.gif)
What is 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE?
The Uses of 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
PD 144418 is high affinity, selective σ1 ligand (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively). PD 144418 displays no significant activity at a wide range of other receptors, ion channels and enzymes. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration.
What are the applications of Application
PD 144418 oxalate is a selective σ1 ligand displaying high selectivity.
Biological Activity
High affinity, selective σ 1 ligand (K i values are 0.08 and 1377 nM for σ 1 and σ 2 respectively). Displays no significant activity at a wide range of other receptors, ion channels and enzymes. Antagonizes mescaline-induced scratching in mice following i.p. administration.
Properties of 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
| Boiling point: | 453.2±45.0 °C(Predicted) |
| Density | 1.067±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | <18.62mg/ml in DMSO |
| form | solid |
| pka | 8.10±0.40(Predicted) |
| color | Off-white |
Safety information for 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
Computed Descriptors for 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
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