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HomeProduct name list1,2,2,6,6-PENTAMETHYLPIPERIDINE

1,2,2,6,6-PENTAMETHYLPIPERIDINE

Synonym(s):Pempidine;PMP

  • CAS NO.:79-55-0
  • Empirical Formula: C10H21N
  • Molecular Weight: 155.28
  • MDL number: MFCD00006493
  • EINECS: 201-211-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 11:59:05
1,2,2,6,6-PENTAMETHYLPIPERIDINE Structural

What is 1,2,2,6,6-PENTAMETHYLPIPERIDINE?

Chemical properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

The Uses of 1,2,2,6,6-PENTAMETHYLPIPERIDINE

1,2,2,6,6-Pentamethylpiperidine is used in the synthesis of BN-fused polycyclic aromatic molecules for potential application to electronic materials and apparatus. In addition, it is a catalyst for th e chemoselective silylation of benzylic alcohols.

The Uses of 1,2,2,6,6-PENTAMETHYLPIPERIDINE

ganglionic blocker, antihypertensive

The Uses of 1,2,2,6,6-PENTAMETHYLPIPERIDINE

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.

Definition

ChEBI: 1,2,2,6,6-pentamethylpiperidine is a member of piperidines.

General Description

The focal 1,8-naphthalimide fluorophores in the antennae were modified with 1,2,2,6,6-pentamethylpiperidine to improve their photostability.

Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.

Properties of 1,2,2,6,6-PENTAMETHYLPIPERIDINE

Melting point: <25 °C
Boiling point: 187-188 °C(lit.)
Density  0.858 g/mL at 25 °C(lit.)
refractive index  n20/D 1.460(lit.)
Flash point: 122 °F
storage temp.  Inert atmosphere,Room Temperature
solubility  Soluble in toluene, dimethylformamide.
form  Liquid
pka 11.25(at 30℃)
color  Clear colorless to light yellow
Sensitive  Air Sensitive
Merck  14,7080
BRN  103806
CAS DataBase Reference 79-55-0(CAS DataBase Reference)
EPA Substance Registry System Piperidine, 1,2,2,6,6-pentamethyl- (79-55-0)

Safety information for 1,2,2,6,6-PENTAMETHYLPIPERIDINE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H226:Flammable liquids
H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1,2,2,6,6-PENTAMETHYLPIPERIDINE

InChIKey XULIXFLCVXWHRF-UHFFFAOYSA-N

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