1,2-Dimethylhydrazine Dihydrochloride
Synonym(s):N,N′-Dimethylhydrazine (sym.) dihydrochloride;1,2-Dimethylhydrazine dihydrochloride
- CAS NO.：306-37-6
- Empirical Formula: C2H10Cl2N2
- Molecular Weight: 133.02
- MDL number: MFCD00012522
- EINECS: 206-183-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is 1,2-Dimethylhydrazine Dihydrochloride?
Chemical properties
white to light yellow crystalline flakes
The Uses of 1,2-Dimethylhydrazine Dihydrochloride
carcinogen
The Uses of 1,2-Dimethylhydrazine Dihydrochloride
1,2-Dimethylhydrazine is a potent carcinogen that acts as a DNA alkylating agent. It is used to induce colon tumors in experimental animals. It was also used in preparation of spiroisoquinolinedione aldose reductase inhibitors.
Definition
ChEBI: A hydrochloride resulting from the reaction of 1,2,dimethylhydrazine with 2 mol eq. of hydrogen chloride.
General Description
Prisms (from water) or white crystalline powder. Distinct amine fishy or ammonia-like odor.
Air & Water Reactions
Extremely hygroscopic. Water soluble.
Reactivity Profile
1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE is a reducing agent. Incompatible with oxidizing agents and bases.
Fire Hazard
Flash point data for 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE are not available; however, 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE is probably combustible.
Biochem/physiol Actions
Induces colon cancer in rats and mice.
Safety Profile
Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. A rocket fuel. When heated to decomposition it emits very toxic fumes of HCl and NOx
Properties of 1,2-Dimethylhydrazine Dihydrochloride
| Melting point: | 167-169 °C (dec.)(lit.) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Crystalline Flakes or Powder |
| color | White to light yellow |
| Water Solubility | almost transparency |
| Merck | 14,3248 |
| BRN | 3905684 |
| InChI | InChI=1S/C2H8N2.2ClH/c1-3-4-2;;/h3-4H,1-2H3;2*1H |
| CAS DataBase Reference | 306-37-6(CAS DataBase Reference) |
| EPA Substance Registry System | 1,2-Dimethylhydrazine dihydrochloride (306-37-6) |
Safety information for 1,2-Dimethylhydrazine Dihydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H350:Carcinogenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for 1,2-Dimethylhydrazine Dihydrochloride
| InChIKey | WLDRFJDGKMTPPV-UHFFFAOYSA-N |
| SMILES | N(C)NC.Cl.Cl |
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