1,2-Dimethylhydrazine Dihydrochloride

Synonym(s):N,N′-Dimethylhydrazine (sym.) dihydrochloride;1,2-Dimethylhydrazine dihydrochloride

CAS NO.：306-37-6
Empirical Formula: C2H10Cl2N2
Molecular Weight: 133.02
MDL number: MFCD00012522
EINECS: 206-183-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-23 09:36:33

1,2-Dimethylhydrazine Dihydrochloride Structural

What is 1,2-Dimethylhydrazine Dihydrochloride?

Chemical properties

white to light yellow crystalline flakes

The Uses of 1,2-Dimethylhydrazine Dihydrochloride

carcinogen

The Uses of 1,2-Dimethylhydrazine Dihydrochloride

1,2-Dimethylhydrazine is a potent carcinogen that acts as a DNA alkylating agent. It is used to induce colon tumors in experimental animals. It was also used in preparation of spiroisoquinolinedione aldose reductase inhibitors.

Definition

ChEBI: A hydrochloride resulting from the reaction of 1,2,dimethylhydrazine with 2 mol eq. of hydrogen chloride.

General Description

Prisms (from water) or white crystalline powder. Distinct amine fishy or ammonia-like odor.

Air & Water Reactions

Extremely hygroscopic. Water soluble.

Reactivity Profile

1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE is a reducing agent. Incompatible with oxidizing agents and bases.

Fire Hazard

Flash point data for 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE are not available; however, 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE is probably combustible.

Biochem/physiol Actions

Induces colon cancer in rats and mice.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. A rocket fuel. When heated to decomposition it emits very toxic fumes of HCl and NOx

Properties of 1,2-Dimethylhydrazine Dihydrochloride

Melting point:	167-169 °C (dec.)(lit.)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Crystalline Flakes or Powder
color	White to light yellow
Water Solubility	almost transparency
Merck	14,3248
BRN	3905684
InChI	InChI=1S/C2H8N2.2ClH/c1-3-4-2;;/h3-4H,1-2H3;2*1H
CAS DataBase Reference	306-37-6(CAS DataBase Reference)
EPA Substance Registry System	1,2-Dimethylhydrazine dihydrochloride (306-37-6)

Safety information for 1,2-Dimethylhydrazine Dihydrochloride

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H350:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.