1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
Synonym(s):1,2-didodecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DLPS; PS(12:0/12:0)
- CAS NO.：208757-51-1
- Empirical Formula: C30H59NNaO10P
- Molecular Weight: 647.76
- MDL number: MFCD00077388
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-22 10:55:35
What is 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT?
Description
DLPS, also known as 1,2-dilauroyl-sn-glycero-3-phospho-L-serine, is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
The Uses of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
12:0 PS may be used:
- in the preparation of large unilamellar vesicles (LUVs)
- as a standard to spike replicas of extracted lipid droplets?and calibration curve generation for lipidomic analysis
- to study its effects on α-secretase activity
General Description
Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.
Biochem/physiol Actions
Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.
Properties of 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
| storage temp. | -20°C |
Safety information for 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
Computed Descriptors for 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
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![1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT](https://img.chemicalbook.in/CAS/GIF/67254-28-8.gif)
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