1,2-DIIODOETHANE

Synonym(s):Ethylene diiodide;Ethylene iodide

CAS NO.：624-73-7
Empirical Formula: C2H4I2
Molecular Weight: 281.86
MDL number: MFCD00001093
EINECS: 210-859-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-28 18:13:10

What is 1,2-DIIODOETHANE?

Chemical properties

dark brown crystals

The Uses of 1,2-DIIODOETHANE

1,2-Diiodoethane is used as C-X bond formation reagent. It is also used as Pharmaceutical intermediates.

The Uses of 1,2-DIIODOETHANE

1,2-Diiodoethane can be used:

To synthesize samarium(II) iodide-water complex (SmI₂-H₂O complex), a single-electron transfer reagent, to further synthesize 3-hydroxy carboxylic acids.
To synthesize derivatives of regioselective homopropargyl alcohols by using sonochemical Barbier-type reaction conditions.
As an iodine source and an effective reagent for the dehydroxy-iodination of alcohols.

Purification Methods

Dissolve it in ether, wash it with saturated aqueous Na2S2O3, dry over MgSO4 and evaporate the ether in vacuo and distil it. Store it in the dark. [Molander et al. J Am Chem Soc 109 453 1987]. [Beilstein 1 IV 169.]

Properties of 1,2-DIIODOETHANE

Melting point:	80-82 °C (lit.)
Boiling point:	200.05°C
Density	2.132 g/mL at 25 °C (lit.)
refractive index	1.8710
storage temp.	2-8°C
form	Crystals or Crystalline Powder
color	Light brown to brown
Specific Gravity	2.132
Water Solubility	Soluble in methanol. Insoluble in water.
Sensitive	Air & Light Sensitive
BRN	1730870
Dielectric constant	3.4（Ambient）
Stability:	Stable, but may discolour on exposure to light. Incompatible with strong bases, strong oxidizing agents.
CAS DataBase Reference	624-73-7(CAS DataBase Reference)
EPA Substance Registry System	Ethane, 1,2-diiodo- (624-73-7)

Safety information for 1,2-DIIODOETHANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.