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HomeProduct name list1,2-DIBENZOYLETHANE

1,2-DIBENZOYLETHANE

  • CAS NO.:495-71-6
  • Empirical Formula: C16H14O2
  • Molecular Weight: 238.28
  • MDL number: MFCD00037818
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 17:06:35
1,2-DIBENZOYLETHANE Structural

What is 1,2-DIBENZOYLETHANE?

The Uses of 1,2-DIBENZOYLETHANE

1,2-Dibenzoylethane is effective in inhibiting the in vivo mammary DMBA-DNA adduct formation. This inhibitory effect on mammary DNA adduct formation was associated with increased liver activities of glutathione S-transferase, QR, and 7-ethoxyresorufin-O-deethylase.

The Uses of 1,2-DIBENZOYLETHANE

It is effective in inhibiting the in vivo mammary DMBA-DNA adduct formation. This inhibitory effect on mammary DNA adduct formation was associated with increased liver activities of glutathione S-transferase, QR, and 7-ethoxyresorufin-O-deethylase.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 28, p. 262, 1980 DOI: 10.1248/cpb.28.262
Journal of the American Chemical Society, 91, p. 687, 1969 DOI: 10.1021/ja01031a029
Tetrahedron Letters, 29, p. 3717, 1988 DOI: 10.1016/S0040-4039(00)82162-0

Properties of 1,2-DIBENZOYLETHANE

Melting point: 144-145°C
Boiling point: 260 °C / 15mmHg
Density  1.116±0.06 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  Dichloromethane (Slightly), DMSO (Slightly), Chloroform (Slightly), Methanol (Sl
form  Solid
color  White to Off-White
Water Solubility  Soluble in acetone. Insoluble in water.
BRN  782937
CAS DataBase Reference 495-71-6(CAS DataBase Reference)
NIST Chemistry Reference 1,4-Butanedione, 1,4-diphenyl-(495-71-6)

Safety information for 1,2-DIBENZOYLETHANE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1,2-DIBENZOYLETHANE

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