11-KETOTESTOSTERONE

Synonym(s):17β-Hydroxy-4-androstene-3,11-dione;17β-Hydroxyandrost-4-ene-3,11-dione;4-Androsten-17β-ol-3,11-dione

CAS NO.：564-35-2
Empirical Formula: C19H26O3
Molecular Weight: 302.41
MDL number: MFCD00198520
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-02 08:55:11

What is 11-KETOTESTOSTERONE?

Description

11-keto Testosterone (CRM) (Item No. 9002654) is a certified reference material that is structurally categorized as an androgen. It is a significant hormone in certain fish, regulating the development of sexual development and behavior. 11-keto Testosterone binds the stickleback kidney androgen receptor (EC₅₀ = 43 nM). 11-keto Testosterone, at 10 nM, significantly activates the human androgen receptor expressed in zebrafish liver cells. This product is intended for research and forensic applications.

The Uses of 11-KETOTESTOSTERONE

A metabolite of Adrenosterone.

Definition

ChEBI: 11-oxotestosterone is a 3-oxo Delta(4)-steroid that is testosterone carrying an additional oxo substituent at position 11. It has a role as an androgen, a marine xenobiotic metabolite and a human metabolite. It is a 3-oxo-Delta(4) steroid, an 11-oxo steroid, an androstanoid and a 17beta-hydroxy steroid. It is functionally related to a testosterone. It derives from a hydride of an androstane.

Biochem/physiol Actions

11-Ketotestosterone is a minor androgen in humans, but a major androgen in fish.

Properties of 11-KETOTESTOSTERONE

Melting point:	183-184 °C(Solv: acetone (67-64-1); hexane (110-54-3))
Boiling point:	476.8±45.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
pka	14.79±0.60(Predicted)
form	Solid
color	White to off-white
InChI	InChI=1/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-14,16-17,22H,3-8,10H2,1-2H3/t13-,14-,16-,17+,18-,19-/s3
EPA Substance Registry System	Androst-4-ene-3,11-dione, 17-hydroxy-, (17.beta.)- (564-35-2)