1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
- CAS NO.：127274-91-3
- Empirical Formula: C61H99ClN2O4
- Molecular Weight: 959.9
- MDL number: MFCD00216701
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-08 21:13:59
What is 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE?
Description
DiD is a lipophilic fluorescent probe. It is rapidly incorporated into phospholipid cell membranes and has been used to label the plasma membrane and endocytic organelles in bovine aorta endothelial cells and rat hippocampal slices. DiD has also been used to assess proliferation in prostate cancer cell lines by flow cytometry, where high DiD-expressing cell populations are associated with lower proliferation. DiD is not cytotoxic and can be detected in subcutaneously implanted PC3 cells in vivo after three weeks. It displays absorption/emission maxima of 650/670 nm, respectively.
The Uses of 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
Fluorescent lipophilic tracer
storage
Store at -20°C
Properties of 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
| storage temp. | −20°C |
| solubility | Soluble in ethanol, methanol, dimethyl
sulfoxide |
| form | crystals |
| color | Dark brown |
| λmax | 644 nm |
| Biological Applications | Detecting cell lysis,microorganisms,nucleic acids,lipid diffusion in giant unilamellar vesicles,lipid diffusion in phospholipid bilayers,lipids and proteins diffusion in membranes; monitoring cell migration |
Safety information for 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
Computed Descriptors for 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
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