1,1'-DIETHYL-2,2'-CYANINE IODIDE

Chemical properties

GOLDEN YELLOW TO DARK RED CRYSTALLINE POWDER

The Uses of 1,1'-DIETHYL-2,2'-CYANINE IODIDE

1,1'-Diethyl-2,2'-cyanine iodide is used to inhibit 1-methyl-4-phenylpyridinium (MPP+), toxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine that induces apoptosis in cerebellar granule neurons (CGNs).

The Uses of 1,1'-DIETHYL-2,2'-CYANINE IODIDE

1,1′-Diethyl-2,2′-cyanine iodide has been used as an absorber in a method to correct the fluorescence excitation-emission matrix (EEM).

The Uses of 1,1'-DIETHYL-2,2'-CYANINE IODIDE

1,1'-Diethyl-2,2'-cyanine Iodide is a potent inhibitor of potent extraneuronal monoamine transporter EMT. It inhibits 1-Methyl-4-phenylpyridinium (MPP+), toxic metabolite of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine that induces apoptosis in cerebellar granule neurons (CGNs).

Definition

ChEBI: 1,1'-diethyl-2,2'-cyanine iodide is a 1,1'-diethyl-2,2'-cyanine halide and an organic iodide salt.

General Description

1,1′-Diethyl-2,2′-cyanine iodide is a quinocyanine dye. This photographic sensitizing dye is mainly used in silver halide photography. 1,1′-Diethyl-2,2′-cyanine iodide dye aggregation in dilute aqueous solution displays red and blue shifted absorption bands.

Purification Methods

It crystallises from EtOH and is dried in a vacuum oven at 80o for 4hours. [Beilstein 23 II 267.]