11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
- CAS NO.:134179-38-7
- Empirical Formula: C8H18N4O3
- Molecular Weight: 218.26
- MDL number: MFCD00269874
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-25 07:34:14
What is 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE?
Description
Amino-PEG3-azide is a bifunctional PEG linker containing an amino group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
Chemical properties
Very Pale Yellow Oil
The Uses of 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
11-Azido-3,6,9-trioxaundecan-1-amine is an azide with polyethylene glycol-like characteristics that can be used to prepare azide-functionalized polymers via click reaction.
The Uses of 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.
What are the applications of Application
Azido-PEG3-amine is a PEG derivative used as a bifunctional, hydrophilic linker
Properties of 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
Boiling point: | 198-202°C |
Density | 1.10 g/mL at 20 °C(lit.) |
refractive index | n |
storage temp. | Amber Vial, Refrigerator, Under Inert Atmosphere |
solubility | miscible with water, polar organic solvents |
form | Viscous Liquid |
color | Yellow to Pale Brown |
BRN | 4745506 |
Stability: | Light Sensitive |
Safety information for 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 |
GHS Hazard Statements |
H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
InChIKey | FPVCVHVTMPCZTH-UHFFFAOYSA-N |
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