1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)
Synonym(s):1-octadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); SOPA; PA(18:0/18:1(9Z))
- CAS NO.：384833-24-3
- Empirical Formula: C39H76NaO8P
- Molecular Weight: 726.99
- MDL number: MFCD02259260
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-08-15 17:38:15
What is 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)?
The Uses of 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)
1-?Stearoyl-?2-?oleoyl-?sn-?glycero-?3-?phosphate (Sodium Salt) is used in the discovery of inhibitory effect of phosphatidylinositol derivatives on P-glycoprotein by virtual screening followed by in vitro cellular studies.
The Uses of 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)
18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)) may be used as a phosphatidic acid (PA) standard to identify the corresponding radiolabeled PA on the thin-layer chromatography (TLC). It may be also used in vesicles for experimental validation in order to identify novel phospholipids capable of inhibiting cellular membrane transportation by (ATP)-binding cassette P-glycoprotein (P-gp).
General Description
18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate) is an unsaturated phosphatidic acid (PA) derivative. PA is present in the biomembranes. It is the simplest glycerophospholipid.
Biochem/physiol Actions
Phosphatidic acid (PA) is the precursor for other phospholipids and acts as a signaling molecule.
Properties of 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)
| storage temp. | -20°C |
Safety information for 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-PHOSPHATE(MONOSODIUM SALT)
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