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HomeProduct name list1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Structural

What is 1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE?

Description

1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC can be formed by incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, as has been demonstrated using neutrophils from monkeys and humans fed a diet enriched in fish oils. 1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC can serve as a substrate for PAF C-16 formation by the remodeling pathway.

What are the applications of Application

1-O-Hexadecyl-2-O-eicosapentaenoyl-sn-glycero-3-phosphorylcholine is a PAF biosynthetic precursor

Definition

ChEBI: 1-hexadecyl-2-[(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl]-sn-glycero-3-phosphocholine is a phosphatidylcholine O-36:5 in which the alkyl and acyl groups specified at positions 1 and 2 are hexadecyl and (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl respectively. It is a phosphatidylcholine O-36:5 and a 2-acyl-1-alkyl-sn-glycero-3-phosphocholine. It is functionally related to an all-cis-5,8,11,14,17-icosapentaenoic acid.

Properties of 1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

storage temp.  −20°C
solubility  acidic PBS: <50 μg/ml (from Docosahexaenoy; basic PBS: <50 μg/ml (from Docosahexaenoy; DMF: >14.3 mg/ml (from Docosahexaen; DMSO: 1 mg/ml; Ethanol: >1.7 mg/ml (from Docosahexaeno; PBS pH 7.2: <50 μg/ml (from Docosahexaenoy
form  Oil.
Sensitive  Hygroscopic

Safety information for 1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
GHS Hazard Statements H225:Flammable liquids
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240:Ground/bond container and receiving equipment.
P241:Use explosion-proof electrical/ventilating/lighting/…/equipment.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Computed Descriptors for 1-O-HEXADECYL-2-EICOSAPENTAENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

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