1-METHYLHISTAMINE DIHYDROCHLORIDE
Synonym(s):1-Methyl-4-(β-aminoethyl)imidazole dihydrochloride
- CAS NO.:6481-48-7
- Empirical Formula: C6H13Cl2N3
- Molecular Weight: 198.09
- MDL number: MFCD00037000
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:41
What is 1-METHYLHISTAMINE DIHYDROCHLORIDE?
Description
1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.
The Uses of 1-METHYLHISTAMINE DIHYDROCHLORIDE
1-Methylhistamine Dihydrochloride is a selective H1-receptor agonists. Also it has depressant effects.
Biochem/physiol Actions
Major metabolite of histamine by histamine N-methyltransferase.
Properties of 1-METHYLHISTAMINE DIHYDROCHLORIDE
Melting point: | >198°C (dec.) |
storage temp. | 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | powder |
color | Pale Yellow |
Stability: | Hygroscopic |
Safety information for 1-METHYLHISTAMINE DIHYDROCHLORIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-METHYLHISTAMINE DIHYDROCHLORIDE
New Products
2,2-diethoxyethanethioamide Tubulysin E (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin H Tubulysin C 1-(1,1-Difluoroethyl)-2-fluorobenzene 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 4,4-DIFLUOROPIPERIDINE tetrahydro-4-methyl-2H-pyran CYCLOBUTYLAMINE HYDROCHLORIDE 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
(S)-2-AMINO-3-(1-METHYL-1H-IMIDAZOL-4-YL)-PROPIONIC ACID 2HCL
N'-Methyl-L-histidine methyl ester
N-TAU-METHYL-D3-HISTAMINE 2HCL
2-AMINO-1-[5-AMINO-1-(PHENYLMETHYL)-1H-IMIDAZOL-4-YL] ETHANONE
1-METHYLHISTAMINE DIHYDROCHLORIDE
H-HIS(BZL)-OME 2 HCL
(S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride
OTAVA-BB BB7020410121
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