1-METHYLADENOSINE

CAS NO.：15763-06-1
Empirical Formula: C11H15N5O4
Molecular Weight: 281.27
MDL number: MFCD00038421
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-28 13:53:24

What is 1-METHYLADENOSINE?

Description

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.

Chemical properties

White to off-white crystalline powder

The Uses of 1-METHYLADENOSINE

1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.

What are the applications of Application

1-Methyladenosine is a modified nucleoside used as a biomarker in the early detection of several forms of cancer.

Definition

ChEBI: A methyladenosine carrying a methyl substituent at position 1.

Properties of 1-METHYLADENOSINE

Melting point:	>217°C (dec.)
Boiling point:	655.4±65.0 °C(Predicted)
Density	1.88±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO (Slightly), Water (Slightly, Sonicated)
form	Solid
pka	13.24±0.70(Predicted)
color	White to Off-White
Stability:	Hygroscopic, Light Sensitive