1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
- CAS NO.:832114-09-7
- Empirical Formula: C16H26BN3O2
- Molecular Weight: 303.21
- MDL number: MFCD05864305
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-30 16:20:48
What is 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE?
The Uses of 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
1-Methyl-4-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]piperazine is used to prepare yrazolopyridine and indazoles as histone lysine methyltransferase EZH2 inhibitors. It is also used to synthesize tetrahydropyrido pyrazines as anaplastic lymphoma kinase inhibitors.
Properties of 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
Melting point: | 125,1-126,8°C |
Boiling point: | 443.5±45.0 °C(Predicted) |
Density | 1.10±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C(protect from light) |
pka | 7.58±0.29(Predicted) |
Safety information for 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
New Products
6-Bromo 2-Iodo Indole Rimegepant Impurity 3 Ivermectin EP Impurity B Fosfomycin EP impurity D Tubulysin A Tubulysin I Tubulysin M (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin F Diethyl Aluminium Cyanide (1.0 M in Toluene) Imeglimin Hydrochloride IH Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH 4-(Azidomethyl)-3-chloropyridine Methyl 4-amino-3-(dihexylamino)benzoate 2-Chloro-3-(chloromethyl)pyridine 4-Bromo-N,N-bis(4-iodophenyl)aniline (1-Isopropyl-1H-pyrazol-5-yl)boronic acid 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 6-bromopyridazin-3-amine (±)-1-Phenylethane ethane sulfonic acidRelated products of tetrahydrofuran
1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
2-(4-ACETYLPIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID, PINACOL ESTER
2-(4-BOC-PIPERAZIN-1-YL)-3-METHYLPYRIDINE-5-BORONIC ACID PINACOL ESTER
1-BENZYL-4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
2-(4-Boc-piperazin-1-yl)-4-methylpyridine-5-boronic acid pinacol ester
2-(4-ETHOXYCARBONYLPIPERAZINE)PYRIDINE-5-BORONIC ACID PINACOL ESTER
4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl
ester
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