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HomeProduct name list1-METHYL-2-INDOLINONE

1-METHYL-2-INDOLINONE

Synonym(s):1-Methyl-1,3-dihydroindol-2-one;1-Methyl-2-indolinone;1-Methyloxindole;Ba 2777;NSC 97219

  • CAS NO.:61-70-1
  • Empirical Formula: C9H9NO
  • Molecular Weight: 147.17
  • MDL number: MFCD00030253
  • EINECS: 612-193-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:06
1-METHYL-2-INDOLINONE Structural

What is 1-METHYL-2-INDOLINONE?

Chemical properties

Light-Yellow Solid

The Uses of 1-METHYL-2-INDOLINONE

1-Methyl-2-oxindole is used in the prevention and therapy of atherosclerotic degradation of arterial walls.

The Uses of 1-METHYL-2-INDOLINONE

1-Methyl-2-indolone is a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents.

The Uses of 1-METHYL-2-INDOLINONE

Reactant for preparation of:

  • Fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching
  • Irreversible Nek2 Kinase Inhibitors
  • Anticancer agents
  • Antimalarial agents
  • Antitimor agents
  • Germination stimulants in plants
  • Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)
  • Retinoic acid analogs
  • Potential anti-multiple sclerosis agents
  • Inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 435, 1985 DOI: 10.1021/ja00288a027
Journal of Heterocyclic Chemistry, 23, p. 1163, 1986 DOI: 10.1002/jhet.5570230439

Properties of 1-METHYL-2-INDOLINONE

Melting point: 85-88 °C(lit.)
Boiling point: 110-120 °C(Press: 1 Torr)
Density  1.167±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka 0.40±0.20(Predicted)
color  White to pink
CAS DataBase Reference 61-70-1(CAS DataBase Reference)

Safety information for 1-METHYL-2-INDOLINONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-METHYL-2-INDOLINONE

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