1-METHYL-2-INDOLINONE
Synonym(s):1-Methyl-1,3-dihydroindol-2-one;1-Methyl-2-indolinone;1-Methyloxindole;Ba 2777;NSC 97219
- CAS NO.：61-70-1
- Empirical Formula: C9H9NO
- Molecular Weight: 147.17
- MDL number: MFCD00030253
- EINECS: 612-193-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:06
What is 1-METHYL-2-INDOLINONE?
Chemical properties
Light-Yellow Solid
The Uses of 1-METHYL-2-INDOLINONE
1-Methyl-2-oxindole is used in the prevention and therapy of atherosclerotic degradation of arterial walls.
The Uses of 1-METHYL-2-INDOLINONE
1-Methyl-2-indolone is a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents.
The Uses of 1-METHYL-2-INDOLINONE
Reactant for preparation of:
- Fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching
- Irreversible Nek2 Kinase Inhibitors
- Anticancer agents
- Antimalarial agents
- Antitimor agents
- Germination stimulants in plants
- Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)
- Retinoic acid analogs
- Potential anti-multiple sclerosis agents
- Inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase
Synthesis Reference(s)
Journal of the American Chemical Society, 107, p. 435, 1985 DOI: 10.1021/ja00288a027
Journal of Heterocyclic Chemistry, 23, p. 1163, 1986 DOI: 10.1002/jhet.5570230439
Properties of 1-METHYL-2-INDOLINONE
| Melting point: | 85-88 °C(lit.) |
| Boiling point: | 110-120 °C(Press: 1 Torr) |
| Density | 1.167±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 0.40±0.20(Predicted) |
| color | White to pink |
| CAS DataBase Reference | 61-70-1(CAS DataBase Reference) |
Safety information for 1-METHYL-2-INDOLINONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-METHYL-2-INDOLINONE
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