1-methyl-1,2,3,4-tetrahydroisoquinoline

CAS NO.：4965-09-7
Empirical Formula: C10H13N
Molecular Weight: 147.22
MDL number: MFCD00798989
EINECS: 803-804-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:39

What is 1-methyl-1,2,3,4-tetrahydroisoquinoline?

Chemical properties

Colorless to pale yellow liquid

The Uses of 1-methyl-1,2,3,4-tetrahydroisoquinoline

1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) is an endogenous antidepressant and parkinsonism-preventing substance that demonstrates neuroprotectiveactivity. Following systemic administration in rats, 1-Methyl-1,2,3,4-tetrahydroisoquinoline produces antidepressant-like effect similar to the effect of imipramine. 1MeTIQ is a reversible short-acting moderate inhibitor of MAO A/B. Also known as 1,2,3,4-Tetrahydro-1-methylisoquinoline, 1MeTIQ. It is an important raw material and intermediate for revaprazan and pharmaceutical.

Definition

ChEBI: 1-methyl-1,2,3,4-tetrahydroisoquinoline is a member of isoquinolines.

Properties of 1-methyl-1,2,3,4-tetrahydroisoquinoline

Boiling point:	119℃/18mm
Density	0.966±0.06 g/cm3(Predicted)
RTECS	NX5087850
refractive index	1.5570 to 1.5610
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
form	Liquid
pka	9.73±0.40(Predicted)
color	Pale yellow
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	4965-09-7

Safety information for 1-methyl-1,2,3,4-tetrahydroisoquinoline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.