1-HYDROXYPHENAZINE
- CAS NO.:528-71-2
- Empirical Formula: C12H8N2O
- Molecular Weight: 196.2
- MDL number: MFCD00059692
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 21:40:10
What is 1-HYDROXYPHENAZINE?
The Uses of 1-HYDROXYPHENAZINE
Hemipyocyanine (1-hydroxyphenazine) is a simple phenazine metabolite produced by several species of Pseudomonas and Streptomyces. Hemipyocyanine exhibits broad spectrum activity with weak antibacterial, antifungal and antiviral activity. In the search for novel actives, hemipyocyanine and related phenazines are important dereplication standards to eliminate leads due to high amounts of weakly potent actives. Hemipyocyanine plays an important role in the biocontrol of plant diseases by some Pseudomonas strains.
The Uses of 1-HYDROXYPHENAZINE
Hemipyocyanine is a phenazine metabolite and important dereplication standard.
What are the applications of Application
Hemipyocyanine is A phenazine metabolite and important dereplication standard
Definition
ChEBI: A phenazine carrying a hydroxy substituent at the 1-position.
Purification Methods
Purify the hydroxyphenazine by chromatography on acidic alumina with *benzene/ether and recrystallise it from aqueous EtOH, *benzene/heptane, then sublime it at 140o/1.5mm. [UV, IR: Badger et al. J Chem Soc 3204 1951, Hegedüs Helv Chim Acta 33 746 1950, Beilstein 23 II 360, 23 III/IV 2753.]
Properties of 1-HYDROXYPHENAZINE
Melting point: | 158°C |
Boiling point: | 333.09°C (rough estimate) |
Density | 1.1788 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | Store at -20°C |
solubility | DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 1 mg/ml |
pka | 6.62±0.30(Predicted) |
form | powder to crystaline |
color | Light yellow to Brown |
Merck | 14,4645 |
Safety information for 1-HYDROXYPHENAZINE
Computed Descriptors for 1-HYDROXYPHENAZINE
New Products
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