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HomeProduct name list1-(DIETHOXYMETHYL)IMIDAZOLE

1-(DIETHOXYMETHYL)IMIDAZOLE

1-(DIETHOXYMETHYL)IMIDAZOLE Structural

What is 1-(DIETHOXYMETHYL)IMIDAZOLE?

The Uses of 1-(DIETHOXYMETHYL)IMIDAZOLE

1-(Diethoxymethyl)imidazole may be used in the preparation of various hydroxy- and amino-functionalized imidazoles, via isoprene-mediated lithiation followed by reaction with an electrophile.

General Description

1-(Diethoxymethyl)imidazole is an orthoamide protected imidazole. The dianion reacts selectively at the 2 position 1-(Diethoxymethyl)imidazole is a 1-substituted imidazoles. Isoprene-mediated lithiation of 1-(diethoxymethyl)imidazole, leads to the preparation of the corresponding 2-lithio intermediate, which reacts with different electrophiles to afford 2-functionalised imidazoles.

Properties of 1-(DIETHOXYMETHYL)IMIDAZOLE

Boiling point: 52 °C(Press: 0.02 Torr)
Density  1.041 g/mL at 20 °C (lit.)
refractive index  n20/D 1.464
Flash point: 112℃
storage temp.  2-8°C
pka 6.13±0.20(Predicted)
BRN  908482

Safety information for 1-(DIETHOXYMETHYL)IMIDAZOLE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-(DIETHOXYMETHYL)IMIDAZOLE

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