1-Chloro-2-propanol

Synonym(s):Chloropropanol;Propylene chlorohydrin

CAS NO.：127-00-4
Empirical Formula: C3H7ClO
Molecular Weight: 94.54
MDL number: MFCD00004530
EINECS: 204-819-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:23

What is 1-Chloro-2-propanol?

Chemical properties

colourless to light yellow liquid

The Uses of 1-Chloro-2-propanol

1-Chloro-2-propanol has been used as:

chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol
as α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes

What are the applications of Application

1-Chloro-2-propanol is a chlorinated propanol used in chemical synthesis

Definition

ChEBI: 1-chloropropan-2-ol is a secondary alcohol that is isopropanol in which one of the methyl hydrogen atoms is substituted by chlorine. It is an organochlorine compound and a secondary alcohol. It derives from a hydride of a propane.

General Description

Clear colorless to light amber liquid with a mild non residual odor.

Air & Water Reactions

Soluble in water.

Reactivity Profile

May be sensitive to prolonged exposure to light. Incompatible with strong oxidizing agents.

Fire Hazard

1-Chloro-2-propanol is combustible.

Properties of 1-Chloro-2-propanol

Boiling point:	126-127 °C(lit.)
Density	1.111 g/mL at 25 °C(lit.)
refractive index	n20/D 1.439(lit.)
Flash point:	125 °F
storage temp.	Flammables area
Water Solubility	Soluble in water
solubility	Chloroform (Soluble), Methanol (Slightly)
form	clear liquid
pka	14.09±0.20(Predicted)
color	Colorless to Light yellow
Merck	14,7851
BRN	773653
Exposure limits	ACGIH: TWA 1 ppm (Skin)
Stability:	Stable. Flammable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	127-00-4(CAS DataBase Reference)
EPA Substance Registry System	1-Chloro-2-propanol (127-00-4)

Safety information for 1-Chloro-2-propanol

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.