1-CBZ-2-PIPERIDINECARBOXYLIC ACID

CAS NO.：28697-07-6
Empirical Formula: C14H17NO4
Molecular Weight: 263.29
MDL number: MFCD01863568
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is 1-CBZ-2-PIPERIDINECARBOXYLIC ACID?

Chemical properties

White solid

The Uses of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID

1,?2-?Piperidinedicarboxyl?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer.

Properties of 1-CBZ-2-PIPERIDINECARBOXYLIC ACID

Melting point:	110 °C(Solv: ethanol (64-17-5))
Boiling point:	443.9±45.0 °C(Predicted)
Density	1.265±0.06 g/cm3(Predicted)
storage temp.	2-8°C
form	powder to crystal
pka	4.01±0.20(Predicted)
color	White to Almost white

Safety information for 1-CBZ-2-PIPERIDINECARBOXYLIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.