1-Bromo-3,5-dimethoxybenzene

What is 1-Bromo-3,5-dimethoxybenzene?

Pale yellow crystals

1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.

1-Bromo-3,5-dimethoxybenzene may be used to synthesize the following:

bis-[di-(3,5-dimethoxyphenyl)methylcyclopentadienyl]titanium(IV)dichloride,{η⁵- C₅H₄-CH-[C₆H₄-(OCH₃)₂]₂)₂TiCl₂ which can be used as an anti-cancer drug and is obtained via a multistep reaction process
5-bromo-benzene-1,3-diol via demethylation with boron tribromide(BBr₃)
1-bromo-3,5-dimethoxy-2-nitrobenzene via nitration reaction

1-Bromo-3,5-dimethoxybenzene is an intermediate in the synthetic preparation of pharmaceutical inhibitors

1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.

Melting point:	62-66 °C (lit.)
Boiling point:	246.0±20.0 °C(Predicted)
Density	1.412±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in methanol.
form	Crystals or Crystalline Powder
color	White to yellow
CAS DataBase Reference	20469-65-2(CAS DataBase Reference)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.