1-Boc-4-(2-hydroxyethyl)piperidine

Synonym(s):N-(tert-Butoxycarbonyl)-4-piperidineethanol

CAS NO.：89151-44-0
Empirical Formula: C12H23NO3
Molecular Weight: 229.32
MDL number: MFCD03427086
EINECS: 692-472-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

1-Boc-4-(2-hydroxyethyl)piperidine Structural

What is 1-Boc-4-(2-hydroxyethyl)piperidine?

The Uses of 1-Boc-4-(2-hydroxyethyl)piperidine

N-BOC-4-piperidine-β-ethanol is used to prepare anilinoquinazoline VEGF receptor tyrosine kinase inhibitors with antitumor activities. It is also used to synthesize 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists with antiviral activities.

Properties of 1-Boc-4-(2-hydroxyethyl)piperidine

Boiling point:	120-150 °C/0.5 mmHg (lit.)
Density	1.043 g/mL at 25 °C (lit.)
refractive index	n20/D 1.4730(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	15.10±0.10(Predicted)
color	Colourless to light yellow
CAS DataBase Reference	89151-44-0(CAS DataBase Reference)

Safety information for 1-Boc-4-(2-hydroxyethyl)piperidine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.