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HomeProduct name list1-Boc-3-(cyanomethylene)azetidine

1-Boc-3-(cyanomethylene)azetidine

1-Boc-3-(cyanomethylene)azetidine Structural

What is 1-Boc-3-(cyanomethylene)azetidine?

The Uses of 1-Boc-3-(cyanomethylene)azetidine

1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.

Properties of 1-Boc-3-(cyanomethylene)azetidine

Boiling point: 309.7±35.0 °C(Predicted)
Density  1.215
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
form  powder to crystal
pka -1.88±0.20(Predicted)
color  White to Orange to Green

Safety information for 1-Boc-3-(cyanomethylene)azetidine

Computed Descriptors for 1-Boc-3-(cyanomethylene)azetidine

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