1-BENZYL 2-METHYL (S)-(-)-1,2-AZIRIDINEDICARBOXYLATE

CAS NO.：104597-98-0
Empirical Formula: C12H13NO4
Molecular Weight: 235.24
MDL number: MFCD06799020
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 1-BENZYL 2-METHYL (S)-(-)-1,2-AZIRIDINEDICARBOXYLATE?

Description

Methyl (S)-(–)-N-Z-aziridine-2-carboxylate is a chiral building block that is commonly used in the organic stereoselective synthesis of various compounds, including anticancer agents, antibiotics, and enzyme inhibitors.

The Uses of 1-BENZYL 2-METHYL (S)-(-)-1,2-AZIRIDINEDICARBOXYLATE

Like aziridine carboxylic acid ester derivative, (S)-1-Benzyl 2-methyl aziridine-1,2-dicarboxylate can be used for the synthetic application of chiral aziridine via esterification.

What are the applications of Application

A reagent

Properties of 1-BENZYL 2-METHYL (S)-(-)-1,2-AZIRIDINEDICARBOXYLATE

Boiling point:	160-165 °C/2 mmHg (lit.)
Density	1.19 g/mL at 25 °C (lit.)
refractive index	n20/D 1.519(lit.)
Flash point:	110 °C
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Soluble), Dichloromethane
form	Oil
pka	-5.65±0.40(Predicted)
color	Colourless
optical activity	[α]20/D 25°, c = 1 in toluene

Safety information for 1-BENZYL 2-METHYL (S)-(-)-1,2-AZIRIDINEDICARBOXYLATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.