1-(5-Methyl-2-thienyl)ethan-1-one
- CAS NO.:13679-74-8
- Empirical Formula: C7H8OS
- Molecular Weight: 140.2
- MDL number: MFCD00014529
- EINECS: 237-181-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-21 22:12:10
What is 1-(5-Methyl-2-thienyl)ethan-1-one?
Chemical properties
white to light yellow crystal powder
The Uses of 1-(5-Methyl-2-thienyl)ethan-1-one
2-Acetyl-5-methylthiophene may be used in the preparation of:
- 2-ethyl-5-methylthiophene
- (5-methylthiophen-2-yl)glyoxal
- (2E)-1-(5-methylthiophen-2-yl)-3-(pyridin-3-yl)prop-2-en-1-one
- ethyl 3-(5-methylthiophen-2-yl)-3-oxopropanoate
Definition
ChEBI: 2-acetyl-5-methylthiophene is a thiophene that is substituted by acetyl and methyl groups at positions 2 and 5, respectively. It has a role as a flavouring agent. It is an aromatic ketone, a member of thiophenes and a methyl ketone.
General Description
2-Acetyl-5-methylthiophene is a volatile organic compound formed during the reaction between L-cysteine and dihydroxyacetone in glycerine or triglyceride solvent system. It can be prepared by reacting 2-methylthiophene with acetic anhydride. 2-Acetyl-5-methylthiophene undergoes palladium-catalyzed cross-coupling reaction with aryl bromides to form C-4 arylated product. It reacts with 1,2-bis(5-formyl-2-methylthiophen-3-yl)cyclopentene via Aldol condensation to form a chalcone with photochromic property. The standard molar enthalpies of combustion, formation and vaporization of 2-acetyl-5-methylthiophene are 4341.9 ± 1.8kJ/mol, 158.0 ± 2.1kJ/mol and 62.0 ± 2.6kJ/mol, respectively.
Safety Profile
A poison by intraperitoneal route. A flammable liquid. When heated to decomposition it emits toxic vapors of SOx.
Properties of 1-(5-Methyl-2-thienyl)ethan-1-one
Melting point: | 24-28 °C(lit.) |
Boiling point: | 65-67 °C1 mm Hg(lit.) |
Density | 1.106 g/mL at 25 °C(lit.) |
refractive index | n |
FEMA | 4643 | 2-ACETYL-5-METHYLTHIOPHENE |
Flash point: | >230 °F |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
form | Low Melting Crystalline Mass, Powder or Crystals |
color | White to pale yellow |
Specific Gravity | 1.119 |
Odor | at 1.00 % in propylene glycol. sweet spicy honey hawthorn almond acacia hyacinth caramellic graham cracker |
Sensitive | Light Sensitive |
JECFA Number | 2107 |
BRN | 110854 |
CAS DataBase Reference | 13679-74-8(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Acetyl-5-methylthiophene(13679-74-8) |
Safety information for 1-(5-Methyl-2-thienyl)ethan-1-one
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P501:Dispose of contents/container to..… |
Computed Descriptors for 1-(5-Methyl-2-thienyl)ethan-1-one
New Products
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