1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE

CAS NO.：2047-91-8
Empirical Formula: C11H11N
Molecular Weight: 157.21
MDL number: MFCD00225387
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:37

What is 1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE?

The Uses of 1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE

• ;Reactant for thionium species-mediated functionalization at the 2α-position of indoles1• ;Reactant for preparation of tetramethylpiperidine-1-oxoammonium salts as oxidants2

The Uses of 1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE

1,2,3,4-Tetrahydrocyclopent[b]indole is used in the synthesis of BACE inhibitors. Also used to synthesize benzazocinecarboxylic acids as potential antiinflammatory agents.

The Uses of 1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE

Reactant for thionium species-mediated functionalization at the 2α-position of indoles
Reactant for preparation of tetramethylpiperidine-1-oxoammonium salts as oxidants

General Description

1,2,3,4-Tetrahydrocyclopent[b] indole undergoes reduction in the presence of Pd/C and hydrogen gas to yield 1,2,3,3a,4,8b-hexahydrocyclopent[b]indole.

Properties of 1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE

Melting point:	100.5-105.5 °C(lit.)
Boiling point:	160-162 °C(Press: 1 Torr)
Density	1.200±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Chloroform, Methanol
pka	17.83±0.20(Predicted)
form	powder to crystaline
color	Light yellow to Brown
λmax	230nm(EtOH aq.)(lit.)

Safety information for 1 2 3 4-TETRAHYDROCYCLOPENT(B) INDOLE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.