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HomeProduct name list(+)-PINORESINOL

(+)-PINORESINOL

  • CAS NO.:487-36-5
  • Empirical Formula: C20H22O6
  • Molecular Weight: 358.39
  • MDL number: MFCD07784516
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 15:53:33
(+)-PINORESINOL Structural

What is (+)-PINORESINOL?

Description

(+)-Pinoresinol is a lignan that has been found in Forsythia and virgin olive oils and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase (IC50s = 492 and 34.3 μM in Baker’s yeast and rat small intestine, respectively). (+)-Pinoresinol scavenges ABTS , but not 2,2-diphenyl-1-picrylhydrazyl (DPPH; ), radicals in cell-free assays (IC50s = 13.43 and >200 μg/ml, respectively). It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37, cells with IC50 values of 29.35, 62.35, 75.32, >80, and >80 μM, respectively. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells (EC50 = 6.96 μM) and inhibits LPS-induced nitric oxide production in RAW 264.7 cells (IC50 = 7.89 μM).

The Uses of (+)-PINORESINOL

(+)-Pinoresinol is a lignan found in olive oil and in other plants. This phenolic compound was reported to have antioxidant and anticancer potential.

Definition

ChEBI: An enantiomer of pinoresinol having (+)-1S,3aR,4S,6aR-configuration.

Properties of (+)-PINORESINOL

Melting point: 112 °C
Boiling point: 556.5±50.0 °C(Predicted)
Density  1.385 g/cm3
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO: ≥6mg/mL
form  Solid
pka 9.54±0.35(Predicted)
color  white to tan

Safety information for (+)-PINORESINOL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (+)-PINORESINOL

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