(-)-O-ACETYL-L-MALIC ANHYDRIDE

Synonym(s):(S)-3-Acetoxy-dihydro-2,5-furandione;O-Acetyl-L-malic anhydride

CAS NO.：59025-03-5
Empirical Formula: C6H6O5
Molecular Weight: 158.11
MDL number: MFCD00082708
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:36

(-)-O-ACETYL-L-MALIC ANHYDRIDE Structural

What is (-)-O-ACETYL-L-MALIC ANHYDRIDE?

Chemical properties

White Crystalline Solid

The Uses of (-)-O-ACETYL-L-MALIC ANHYDRIDE

(-)-O-Acetyl-L-Malic Anhydride can be used as intermediates for detergents via O-acetylmalic acid amides. Regioselective ring opening of malic acid anhydrides by carbon nucleophiles

The Uses of (-)-O-ACETYL-L-MALIC ANHYDRIDE

(S)-(-)-2-Acetoxysuccinic anhydride is used as intermediates for detergents via O-acetylmalic acid amides. Regioselective ring opening of malic acid anhydrides by carbon nucleophiles.

Purification Methods

Recrystallise it from Ac2O and dry it in a vacuum over KOH, or by washing it with dry Et2O due to its deliquescent nature. [Jones J Chem Soc 788 1933, Henrot et al. Synth Commun 16 183 1986, Shiuey et al. J Org Chem 52 1040 1988, RS: Cohen et al. J Am Chem Soc 88 5306 1966.]

Properties of (-)-O-ACETYL-L-MALIC ANHYDRIDE

Melting point:	54-56 °C(lit.)
Boiling point:	296.6±33.0 °C(Predicted)
Density	1.38±0.1 g/cm3(Predicted)
refractive index	-25.5 ° (C=5, CHCl3)
storage temp.	Inert atmosphere,Room Temperature
solubility	Dichloromethane, DMF, Ethyl Acetate
form	Powder
color	White Crystalline
optical activity	[α]20/D 27°, c = 1 in chloroform
Water Solubility	Reacts in water.
Sensitive	Moisture Sensitive
BRN	82504
Stability:	Stable. Incompatible with strong oxidizing agents. Sensitive to moisture.
CAS DataBase Reference	59025-03-5(CAS DataBase Reference)

Safety information for (-)-O-ACETYL-L-MALIC ANHYDRIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.