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HomeProduct name list(+)-MK 801 MALEATE

(+)-MK 801 MALEATE

Synonym(s):(5R,10S)-(–)-5-Methyl-10,11-dihydro-5H-dibenzo-[a,d]-cyclo-hepten-5,10-imine hydrogen maleate;(5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate;Dizocilpine hydrogen maleate

(+)-MK 801 MALEATE Structural

What is (+)-MK 801 MALEATE?

The Uses of (+)-MK 801 MALEATE

Biochemical probe for NMDA receptors.

What are the applications of Application

(?)-MK 801 maleate is an NMDA receptor antagonist

General Description

(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.

Biological Activity

Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ).

Biochem/physiol Actions

Less active enantiomer of (+)-MK-801 hydrogen maleate

Properties of (+)-MK 801 MALEATE

Melting point: 68.5-69.5°
alpha  589 -160.8° (c = 0.032 g/2 ml ethanol)
storage temp.  room temp
solubility  DMSO: >20mg/mL
form  solid
color  white
optical activity [α]25/D 117.7°, c = 1 in methanol(lit.)

Safety information for (+)-MK 801 MALEATE

Computed Descriptors for (+)-MK 801 MALEATE

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