(+)-MK 801 MALEATE
Synonym(s):(5R,10S)-(–)-5-Methyl-10,11-dihydro-5H-dibenzo-[a,d]-cyclo-hepten-5,10-imine hydrogen maleate;(5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate;Dizocilpine hydrogen maleate
- CAS NO.：77086-19-2
- Empirical Formula: C16H15N
- Molecular Weight: 221.3
- MDL number: MFCD00082466
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (+)-MK 801 MALEATE?
The Uses of (+)-MK 801 MALEATE
Biochemical probe for NMDA receptors.
What are the applications of Application
(?)-MK 801 maleate is an NMDA receptor antagonist
General Description
(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.
Biological Activity
Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ).
Biochem/physiol Actions
Less active enantiomer of (+)-MK-801 hydrogen maleate
Properties of (+)-MK 801 MALEATE
| Melting point: | 68.5-69.5° |
| alpha | 589 -160.8° (c = 0.032 g/2 ml ethanol) |
| storage temp. | room temp |
| solubility | DMSO: >20mg/mL |
| form | solid |
| color | white |
| optical activity | [α]25/D 117.7°, c = 1 in methanol(lit.) |
Safety information for (+)-MK 801 MALEATE
Computed Descriptors for (+)-MK 801 MALEATE
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![10,11-DIHYDRO-5 H-DIBENZO[A,D]CYCLOHEPTENE](https://img.chemicalbook.in/CAS/GIF/833-48-7.gif)
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