Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(+)-MENTHOL

(+)-MENTHOL

Synonym(s):(+)-Menthol;(1S,2R,5S)-2-Isopropyl-5-methylcyclohexanol

  • CAS NO.:15356-60-2
  • Empirical Formula: C10H20O
  • Molecular Weight: 156.27
  • MDL number: MFCD00062983
  • EINECS: 239-387-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-09 19:38:33
(+)-MENTHOL Structural

What is (+)-MENTHOL?

Description

(+)-Menthol is a monoterpene alcohol that has been found in Cannabis and has antifungal activity. It inhibits the growth of F. verticillioides (MIC = 1.5 mM). Unlike (–)-menthol, (+)-menthol does not exhibit analgesia, antibacterial, anticancer, or cholinesterase inhibitory activities.

Chemical properties

(+)-MENTHOL is white low melting solid

The Uses of (+)-MENTHOL

(+)-MENTHOL is used for oral gel patch or film containing herb extracts or Chinese medicine, fruit extract, spearmint, and menthol for smoking cessation.

The Uses of (+)-MENTHOL

(1S,2R,5S)-(+)-menthol can undergo acylation with acid anhydrides in the presence of trimethylsilyl trifluoromethanesulfonate to form the corresponding acylated products.

Definition

ChEBI: (+)-menthol is a p-menthan-3-ol which has (1S,2R,5S)-stereochemistry. In contrast to (-)-menthol, the (+)-enantiomer occurs only rarely in nature. It is an enantiomer of a (-)-menthol.

General Description

(1S,2R,5S)-(+)-menthol is a chiral secondary alcohol. Its alcohol group can be protected as 2-tetrahydrofuranyl ether by reacting with bromotrichloromethane and tetrahydrofuran.

Synthesis

Prod.: by Meerwein-Ponndorf-Verley reduction of l-Menthone, resuhing in approximately two-thirds d-Neomenthol plus one-third i-Menthol. It can also be produced by reduction of d-Menthone.

Properties of (+)-MENTHOL

Melting point: 43-44 °C (lit.)
Boiling point: 103-104 °C/9 mmHg (lit.)
Density  0.890
vapor pressure  0.8 mm Hg ( 20 °C)
refractive index  50 ° (C=10, EtOH)
Flash point: 196 °F
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka 15.30±0.60(Predicted)
color  Colourless to Off-White Oil to Low-Melting
Odor mentholic
optical activity [α]23/D +48°, c = 10 in ethanol
Water Solubility  Soluble in methanol (almost transparency), chloroform, alcohols, water (456 mg/L at 25°C), and ether.
BRN  1902292
Dielectric constant 3.2(Ambient)
CAS DataBase Reference 15356-60-2(CAS DataBase Reference)
EPA Substance Registry System Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5S)- (15356-60-2)

Safety information for (+)-MENTHOL

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (+)-MENTHOL

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.