(-)-BICUCULLINE METHOCHLORIDE
- CAS NO.:53552-05-9
- Empirical Formula: C21H20ClNO6
- Molecular Weight: 417.84
- MDL number: MFCD00078981
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24

What is (-)-BICUCULLINE METHOCHLORIDE?
The Uses of (-)-BICUCULLINE METHOCHLORIDE
(-)-Bicuculline Methochloride is a GABA receptor inhibitor. Convulsant.
What are the applications of Application
(?)-Bicuculline methochloride is a water-soluble GABAA antagonist
Biological Activity
Methochloride salt of (+)-bicuculline ([R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one ). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.
Properties of (-)-BICUCULLINE METHOCHLORIDE
storage temp. | Store at RT |
solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml |
form | Powder |
Water Solubility | Soluble to 100 mM in water |
Safety information for (-)-BICUCULLINE METHOCHLORIDE
Computed Descriptors for (-)-BICUCULLINE METHOCHLORIDE
New Products
DL-Lactide L-Lactide PLGA 50:50 – PEG, DLG501P1 ,M.W:PLGA (Mw) : ~10,000 da, PEG (Mw) : ~1500 da Poly(DL-Lactide)-co-Glycolide, DLG852A, M.W:7,000 - 17,000 da, I.V: 0.16 - 0.24 dL/g Polycaprolactone, CL10015 , M.W: 190,000 – 240,000 da , I.V: 1.30 – 1.70 dL/g Lawesson’s Reagent methyl vinyl sulfone Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-, (2E)-2-butenedioate (1:1) 5-NITRONICOTINIC ACID 3-Pyridineacetonitrile, α-amino-, hydrochloride (1:1) TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN (1-Cyano-cyclobutyl)-carbamic acid tert-butyl ester ETHYL 2-[(3-FORMYL-4-ISOPROPOXYPHENYL]-4- METHY-1,3-THIAZOLE-5-CARBOXYLATE ROPIVACAINE USP RELATED COMPOUND B (HCL SALT) OPEN RING DESULFATED AZTREONAM (E-ISOMER) / AZTREONAM USP RELATED COMPOUND B HYOSCYAMINE RELATED COMPOUND A HYDROCHLORIDE ASCORBIC ACID IMPURITY D ((3S,4R,5S)-METHYL 3,4,5,6-TETRAHYDROXY-2-OXOHEXANOATE) LUMEFANTRINE N-OXIDE (2 BTL) Linagliptin (S)-(+)-N-(2,3-Epoxypropyl)phthalimide or (S)-N-Glycidylphthalimide 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole 4-(2-chloroethyl)-α,α-dimethyl-) Benzeneacetic acid 4-Nitrophenyl Chloroformate 2-(4-Bromophenyl)-2-methylpropanoic acidRelated products of tetrahydrofuran








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