Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(-)-BETA-HYDRASTINE

(-)-BETA-HYDRASTINE

Synonym(s):(1R,9S)-(−)-β-Hydrastine

  • CAS NO.:118-08-1
  • Empirical Formula: C21H21NO6
  • Molecular Weight: 383.39
  • MDL number: MFCD00152561
  • EINECS: 204-233-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 19:05:58
(-)-BETA-HYDRASTINE Structural

What is (-)-BETA-HYDRASTINE?

Description

(1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 μM in PC12 cells) by inhibiting tyrosine hydroxylase activity. It inhibits dopamine release with an IC50 value of 66.5 μM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.

The Uses of (-)-BETA-HYDRASTINE

anesthetic (local), antiarrhythmic

The Uses of (-)-BETA-HYDRASTINE

(-)-β-Hydrastine is an inhibitor of Dopamine biosynthesis.

What are the applications of Application

(1R,9S)-(–)-β-Hydrastine is an inhibitor of Dopamine biosynthesis

Definition

ChEBI: A natural product found in Hydrastis canadensis.

Properties of (-)-BETA-HYDRASTINE

Melting point: 132℃
Boiling point: 510.32°C (rough estimate)
alpha  D20 -50° (c = 0.3 in abs alc)
Density  1.339±0.06 g/cm3 (20 ºC 760 Torr)
refractive index  1.5614 (estimate)
storage temp.  −20°C
solubility  DMF: 10 mg/ml; DMSO: 10 mg/ml
form  A crystalline solid
pka 7.8(at 25℃)
color  White to light yellow
Water Solubility  30mg/L(20 ºC)
CAS DataBase Reference 118-08-1(CAS DataBase Reference)

Safety information for (-)-BETA-HYDRASTINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral

Computed Descriptors for (-)-BETA-HYDRASTINE

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.