(+/-)AMETHOPTERIN
- CAS NO.：60388-53-6
- Empirical Formula: C20H22N8O5
- Molecular Weight: 454.44
- MDL number: MFCD00064369
- EINECS: 262-213-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is (+/-)AMETHOPTERIN?
Chemical properties
yellow to orange crystalline powder
The Uses of (+/-)AMETHOPTERIN
(+/-)Amethopterin is a folic acid antagonist and anticancer agent.
The Uses of (+/-)AMETHOPTERIN
Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist
The Uses of (+/-)AMETHOPTERIN
Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
What are the applications of Application
(±)Amethopterin is a folic acid and aminopterin derivative, folic acid antagonist, and anticancer agent.
Definition
ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.
Properties of (+/-)AMETHOPTERIN
| Melting point: | 195 °C (dec.)(lit.) |
| Density | 1.536±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C. |
| form | powder |
| pka | 3.47±0.10(Predicted) |
| color | yellow |
Safety information for (+/-)AMETHOPTERIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)AMETHOPTERIN
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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