(+/-)-8-PRENYLNARINGENIN
- CAS NO.：68682-02-0
- Empirical Formula: C20H20O5
- Molecular Weight: 340.37
- MDL number: MFCD21364781
- EINECS: 245-096-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:41
What is (+/-)-8-PRENYLNARINGENIN?
Description
(±)-8-Prenylnaringenin ((±)-8-PN) is a prenylflavonoid with potent estrogenic activity that can be isolated from hops. It inhibits both isoforms of the human estrogen receptor (ER; IC50s = 57 and 68 nM for ERα and ERβ, respectively). (±)-8-PN is effective in vivo, suppressing loss of bone mineral density in ovariectomized rats and blocking changes in tail skin temperature in a rat model of postmenopausal hot flashes.
The Uses of (+/-)-8-PRENYLNARINGENIN
8-Prenylnaringenin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding.
What are the applications of Application
8-Isopentenylnaringenin is a selective, non-steroidal estrogen receptor α (ERα) ligand
Definition
ChEBI: Rac 8-Prenylnaringenin is a member of flavanones.
Properties of (+/-)-8-PRENYLNARINGENIN
| Melting point: | 183-184 °C |
| Boiling point: | 597.6±50.0 °C(Predicted) |
| Density | 1.314±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Light yellow powder |
| pka | 7.70±0.40(Predicted) |
| color | Off-White to Pale Yellow |
| Stability: | Light Sensitive |
Safety information for (+/-)-8-PRENYLNARINGENIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for (+/-)-8-PRENYLNARINGENIN
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