CHEMICAL AND PHYSICAL PROPERTIES
Melting Point | 200-216 |
---|---|
Solubility | Practically insoluble |
COMPUTED DESCRIPTORS
Molecular Weight | 428.9 g/mol |
---|---|
XLogP3 | 2.7 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 2 |
Exact Mass | 428.1565934 g/mol |
Monoisotopic Mass | 428.1565934 g/mol |
Topological Polar Surface Area | 74.6 Ų |
Heavy Atom Count | 29 |
Formal Charge | 0 |
Complexity | 843 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 9 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Ulobetasol is a highly potent corticosteroid. It is structurally related to [clobetasol]. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses. Ulobetasol was granted FDA approval on 17 December 1990.