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98048-07-8

98048-07-8 structural image
Product Name: Fomidacillin
Formula: C24H28N6O10S
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COMPUTED DESCRIPTORS

Molecular Weight 592.6 g/mol
XLogP3 0.1
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 7
Exact Mass 592.15876228 g/mol
Monoisotopic Mass 592.15876228 g/mol
Topological Polar Surface Area 251 Ų
Heavy Atom Count 41
Formal Charge 0
Complexity 1170
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Fomidacillin is a semisynthetic beta-lactamase-stable penicillin with antibacterial activity. Fomidacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.