92665-29-7
Product Name:
Cefprozil
Formula:
C18H19N3O5S
Synonyms:
(6R,7R)-7-[(R)-2-Amino-2-(p-hydroxyphenyl)acetamido]-8-oxo-3-propenyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate;Cefprozil monohydrate
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CHEMICAL AND PHYSICAL PROPERTIES
Melting Point | 218-225 °C |
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Solubility | 55 mg/L |
LogP | 0.6 |
COMPUTED DESCRIPTORS
Molecular Weight | 389.4 g/mol |
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XLogP3 | -1.4 |
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 5 |
Exact Mass | 389.10454189 g/mol |
Monoisotopic Mass | 389.10454189 g/mol |
Topological Polar Surface Area | 158 Ų |
Heavy Atom Count | 27 |
Formal Charge | 0 |
Complexity | 699 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 1 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Cefprozil is a semisynthetic, second-generation cephalosporin, with prop-1-enyl and (R)-2-amino-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used to treat bronchitis as well as ear, skin and other bacterial infections. It has a role as an antibacterial drug. It is a cephalosporin and a semisynthetic derivative.