89796-99-6
![89796-99-6 structural image](https://img.chemicalbook.in/CAS/GIF/89796-99-6.gif)
Product Name:
Aceclofenac
Formula:
C16H13Cl2NO4
Synonyms:
2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester;;Aceclofenac
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Melting Point | 149-153 |
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Solubility | >53.1 [ug/mL] (The mean of the results at pH 7.4) |
LogP | 2.17 |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Environment GHS09 |
GHS Hazard Statements |
H301:Acute toxicity,oral H319:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 354.2 g/mol |
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XLogP3 | 4.3 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 5 |
Rotatable Bond Count | 7 |
Exact Mass | 353.0221633 g/mol |
Monoisotopic Mass | 353.0221633 g/mol |
Topological Polar Surface Area | 75.6 Ų |
Heavy Atom Count | 23 |
Formal Charge | 0 |
Complexity | 411 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Aceclofenac is a monocarboxylic acid that is the carboxymethyl ester of diclofenac. A non-steroidal anti-inflammatory drug related to diclofenac, it is used in the management of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It has a role as an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a non-steroidal anti-inflammatory drug and a non-narcotic analgesic. It is a monocarboxylic acid, a carboxylic ester, a secondary amino compound, an amino acid and a dichlorobenzene. It is functionally related to a diclofenac.