COMPUTED DESCRIPTORS
| Molecular Weight | 704.6 g/mol |
|---|---|
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 15 |
| Rotatable Bond Count | 15 |
| Exact Mass | 704.18669111 g/mol |
| Monoisotopic Mass | 704.18669111 g/mol |
| Topological Polar Surface Area | 208 Ų |
| Heavy Atom Count | 52 |
| Formal Charge | 0 |
| Complexity | 1240 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Glunicate is a long-acting nicotinic acid derivative with antilipidemic activity. Glunicate has more prolonged activity on plasma free fatty acids and triglycerides, with longer lasting and more intense activity on plasma cholesterol than nicotinic acid or its derivative, niceritrol. In animal models glunicate showed dose-dependent protection of the arterial wall from atheromatous lesions and from cholesterol and collagen accumulation. These effects were independent of its effects on lowering plasma lipid levels.